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Uric Acid, 24-Hour Urine Collection with Differential Measurement

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of uric acid excreted in your urine over a full day. Uric acid is a waste product your body creates when breaking down certain foods and substances.

Quick summary

["Understanding your uric acid excretion helps assess kidney function and potential risks for conditions like gout or kidney stones."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
101735-9
Short code
Urate Cry 24h EngDiff Ur
Synonyms
Urate Cry 24h EngDiff Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like joint pain, kidney problems, or if you’re at risk for conditions linked to high uric acid levels. It can also help diagnose or monitor certain metabolic disorders.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours, starting and ending with your first morning urine. Store the sample at room temperature and bring the entire collection to the lab. Follow any specific instructions your provider gives you.

How the Test Works

The test measures the total uric acid in your urine over a day. Some labs may also analyze the urine for patterns of uric acid excretion, such as whether it’s consistently high or varies throughout the day.

What the Results Mean

Results help determine if your kidneys are effectively removing uric acid or if levels are unusually high. Elevated results may indicate conditions like gout, kidney disease, or certain genetic disorders.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Uric Acid and Kidney Health

Short name

Uric Acid (24h Urine)

Frequently asked questions

What causes high uric acid levels in urine?
High uric acid levels in urine can result from diet (e.g., high-purine foods), kidney issues, or metabolic disorders. It may also be linked to medications, dehydration, or genetic predispositions.
What should I do if my uric acid levels are high?
If your results are elevated, your provider may recommend lifestyle changes (like reducing purine-rich foods), medications, or further testing to address the underlying cause, such as kidney function or gout.
Does diet affect this test?
Yes, diet can influence uric acid levels. Avoid high-purine foods (e.g., organ meats, shellfish) and limit alcohol and sugary drinks during your 24-hour urine collection to get more accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy