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Uun12hurmrate

Published: July 31, 2026Updated: August 16, 2026

A test that measures the amount of urea nitrogen in your urine over a 12-hour period to evaluate kidney function and protein metabolism.

Quick summary

{"Measures how much urea nitrogen (a waste product) your kidneys excrete in 12 hours","Helps doctors assess how well your kidneys are filtering waste from your blood","Used to diagnose and monitor kidney disease and evaluate protein metabolism","Involves collecting all urine produced over a 12-hour period","Results are affected by diet, kidney function, and certain medical conditions"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24465-7
Short code
UUN12
Synonyms
UUN 12h Ur-mRate
Category
chemistry
Sample
urine
Container
Sterile plastic urine container (24-hour or timed collection container)
Units
not specified
Ref low
6
Ref high
10
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Enzymatic ultraviolet (UV) method or colorimetric assay using urease with glutamate dehydrogenase
CPT
84540
SNOMED
314795006
Specimen volume
Complete 12-hour collection, typically 500-2000 mL; record total volume
Stability
Refrigerated (2-8°C): up to 7 days; Room temperature (20-25°C): up to 24 hours; Frozen (-20°C): stable for several weeks
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–72 hours
Order
routine

What is this test?

The 12-hour urine urea nitrogen test measures the amount of urea nitrogen that your kidneys excrete in urine over a 12-hour period. Urea is a waste product formed in your liver when protein is broken down. Your kidneys normally filter urea from the blood and excrete it in urine. This test helps doctors understand how well your kidneys are working and how your body is processing protein.

How is the test performed?

You will receive a special container from your healthcare provider. For 12 hours (usually overnight), you will collect all urine you produce in the container. It's important to collect every drop during this time period for accurate results. The container should be kept refrigerated or in a cool place. After the 12-hour collection period is complete, return the container to your lab or healthcare provider as instructed.

How to prepare for the test

Your doctor may ask you to avoid certain foods, medications, or supplements before the test. You should continue your normal diet unless instructed otherwise. It's important to drink normal amounts of fluids unless told to do otherwise. Tell your doctor about all medications you are taking, as some can affect test results.

What do the results mean?

Normal values vary by lab, but generally range from 12 to 20 grams of urea nitrogen per 24 hours (the test measures half of this for a 12-hour period). Higher than normal levels may indicate kidney problems, high protein intake, or certain conditions. Lower than normal levels may indicate kidney disease, liver disease, or low protein intake. Your doctor will interpret your results based on your overall health and other test results.

Reference range

6-10 g/12 hnot specified

Specimen: urine

Complete timed 12-hour urine collection; no fasting required; dietary protein intake affects results

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Does the test hurt?
No, the test is completely painless. You simply collect your urine in a container as you normally would. There are no needles or invasive procedures involved.
What happens if I miss some urine during the 12-hour collection?
It is very important to collect every drop of urine during the collection period. If you miss some, tell your healthcare provider when you return the sample. They may need to have you repeat the test to get accurate results.
Can I exercise during the collection period?
You should avoid strenuous exercise during the 12-hour collection period, as intense exercise can affect the test results. Continue with normal daily activities unless your doctor instructs otherwise.
How long does it take to get results?
Results are typically available within 1-3 days, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
Do I need to fast before this test?
Fasting is usually not required for this test. However, your doctor may give you specific instructions about diet or medications. Follow any instructions provided by your healthcare team.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy