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Vitamin C (Ascorbic Acid) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin C, an essential antioxidant found in your blood. Vitamin C helps protect cells from damage and supports immune function.

Quick summary

["Vitamin C levels can help assess your antioxidant status and overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99411-1
Short code
VGCC Ab CSF IA-sCnc
Synonyms
VGCC Ab CSF IA-sCnc
Category
electrolyte
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Might This Test Be Done?

Your healthcare provider may order this test to check for vitamin C deficiency, monitor vitamin C levels in certain conditions (like smoking or chronic illness), or evaluate how well your body absorbs or uses vitamin C. It can also be part of broader nutritional assessments or screening for metabolic disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your test involves a fasting sample. Wear comfortable clothing and plan to rest for about 15 minutes after the draw.

What Happens During the Test?

A healthcare professional will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but it typically doesn’t cause significant discomfort. The blood sample will be sent to a lab for analysis.

What Are the Possible Results?

Results are expressed in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). While reference ranges can vary by lab, low levels may indicate deficiency, while very high levels could suggest certain medical conditions or medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low vitamin C levels may signal deficiencies, which can weaken immunity, cause scurvy, or contribute to chronic diseases. High levels might indicate overconsumption, certain genetic disorders, or conditions like hemolytic anemia. Regular monitoring is important for patients with chronic illnesses, smokers, or those with malabsorption issues.

Short name

Serum/Plasma Vitamin C

Frequently asked questions

What causes vitamin C levels to be low?
Vitamin C deficiency is often due to poor diet (lack of fruits/vegetables), certain medical conditions (like Crohn’s disease or celiac disease), smoking, or excessive alcohol use. Rarely, genetic disorders or medications can also affect absorption.
What symptoms might I experience if my vitamin C levels are low?
Symptoms of low vitamin C can include fatigue, gum bleeding, frequent infections, joint pain, or skin problems like bruising or slow wound healing. If you notice these, discuss them with your provider.
Can vitamin C levels be affected by medications?
Yes, some medications (like certain diuretics, chemotherapy drugs, or antibiotics) may interfere with vitamin C metabolism or absorption. Always inform your provider about all medications you’re taking.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy