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Vitamin C (Ascorbic Acid) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin C, a powerful antioxidant, in your blood serum. Vitamin C helps protect cells from damage and supports immune function.

Quick summary

["Vitamin C levels can help assess nutritional status and identify deficiencies or excesses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12724-1
Short code
VGCC IgG Ser-aCnc
Synonyms
VGCC IgG Ser-aCnc
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms of vitamin C deficiency (like fatigue, bruising, or slow wound healing), suspected scurvy, or if you have conditions that affect vitamin absorption (e.g., malabsorption disorders). It may also be done as part of a routine check for nutritional health or before certain treatments.

What to Expect During the Test

A small blood sample is drawn from a vein, usually in your arm. The serum portion of your blood is then analyzed to measure vitamin C levels. This is a quick, painless procedure that typically takes a few minutes.

What the Results Mean

Results help determine if your vitamin C levels are within a healthy range. Low levels may indicate poor diet, malabsorption, or other health issues, while very high levels could suggest supplements or certain medical conditions.

Common Reasons for Testing

This test is often used to diagnose vitamin C deficiency, monitor treatment responses, or check for conditions like scurvy. It can also be part of broader nutritional assessments or before surgeries requiring high vitamin C levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin C Level

Frequently asked questions

What are the normal reference ranges for vitamin C in blood?
Normal reference ranges can vary by lab and may not be widely standardized. Your results will be interpreted by your healthcare provider based on your specific health status, symptoms, and medical history. Deficiencies can lead to weakened immunity, poor wound healing, or other complications, while very high levels may indicate excessive supplementation or certain metabolic conditions.
How often should I get this test?
The frequency depends on your health needs. If you have a known deficiency or condition affecting vitamin C, your doctor may recommend regular testing. Otherwise, it’s usually done as needed for symptoms or specific medical reasons.
Can vitamin C levels change with diet or supplements?
Yes, diet and supplements can significantly affect vitamin C levels. Eating foods rich in vitamin C (like citrus fruits, bell peppers, or leafy greens) or taking supplements can raise your levels. Your healthcare provider may advise adjustments based on your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy