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Vitamin D Binding Protein (DBP) Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin D binding protein in your blood. It helps assess how well vitamin D is transported and utilized in your body.

Quick summary

["Understanding your vitamin D binding protein levels can help evaluate vitamin D metabolism and related health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109124-8
Short code
VGCC-P/Q Bind Ab Msmt Ser
Synonyms
VGCC-P/Q Bind Ab Msmt Ser
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of vitamin D deficiency, kidney disease, or conditions affecting protein metabolism. It may also be part of a broader evaluation for conditions like hypophosphatasia or certain genetic disorders.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, and you’ll rest for a few minutes afterward. If you’re on blood thinners or have a history of bleeding issues, let your provider know.

What the Results Mean

Vitamin D binding protein levels can vary based on factors like kidney function, liver health, and genetic differences. High levels may indicate certain genetic conditions, while very low levels could suggest kidney dysfunction or other metabolic issues. Your results will be interpreted by your healthcare provider in the context of your overall health.

Common Conditions Monitored

This test is often used alongside other vitamin D tests (like 25-hydroxy vitamin D) to diagnose or monitor conditions such as vitamin D deficiency, hypophosphatasia, or hereditary conditions affecting protein metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

DBP Level

Frequently asked questions

What could cause abnormal results?
Abnormal vitamin D binding protein levels can be caused by genetic disorders (e.g., hypophosphatasia), kidney disease, liver disease, or certain medications that affect protein metabolism. High levels may also be seen in conditions like multiple myeloma or other plasma cell disorders.
How often should I get this test?
The frequency of this test depends on your medical condition and healthcare provider’s recommendations. If you have a known genetic condition or chronic kidney disease, your provider may monitor it regularly. Otherwise, it’s usually ordered as needed for specific symptoms or evaluations.
Can diet or supplements affect this test?
Dietary factors like vitamin D intake or protein-rich foods may indirectly influence vitamin D metabolism, but they don’t directly affect vitamin D binding protein levels. Your provider may discuss lifestyle factors if vitamin D or protein metabolism is being evaluated alongside this test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy