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Vitamin K-dependent coagulation factors (screening panel)

Published: August 9, 2026Updated: August 16, 2026

This test measures several blood proteins that help your blood clot normally. Vitamin K is needed for their production.

Quick summary

["Checks if your blood clotting is functioning properly by evaluating key proteins involved in coagulation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97560-7
Short code
VGKC IgG+IgM Ser IA-sCnc
Synonyms
VGKC IgG+IgM Ser IA-sCnc
Category
electrolyte
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This screening panel typically includes tests for factors II (prothrombin), VII (proconvertin), IX (Christmas factor), and X (Stuart-Prower factor). These proteins are essential for blood clotting and are dependent on vitamin K for proper synthesis in your liver.

Why It’s Done

Doctors may order this test if you have bleeding problems, unexplained bruising, excessive bleeding after surgery or childbirth, or if you’re taking blood thinners (like warfarin) and need monitoring. It can also help diagnose conditions like vitamin K deficiency or liver disease.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is collected in a tube and sent to the lab for analysis. This test does not require fasting or special preparation beyond standard blood draw guidelines.

Common Conditions Monitored

This test helps assess bleeding disorders, liver function, and vitamin K status. Abnormal results may indicate issues like clotting factor deficiencies, liver disease, or malabsorption problems that affect vitamin K absorption.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Vitamin K Factors (Screen)

Frequently asked questions

How long will it take to get my results?
Results are typically available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
What does a low or high result mean?
Low levels of these factors may suggest bleeding disorders, liver disease, or vitamin K deficiency. High levels are less common but could indicate certain medications or rare genetic conditions. Your doctor will interpret results in the context of your medical history.
Can I eat or drink before this test?
No special diet is needed for this test. However, if you’re on blood thinners, follow your doctor’s instructions regarding temporary adjustments to your medication.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy