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Vitamin D Binding Protein (DBP) – Serum or Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Vitamin D Binding Protein in your blood. It helps assess how well vitamin D is transported in your body.

Quick summary

["Understanding your DBP levels can support vitamin D metabolism and related health evaluations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1625-3
Short code
Vit A 6h p 5000 U SerPl-mCnc
Synonyms
Vit A 6h p 5000 U SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Vitamin D Binding Protein?

Vitamin D Binding Protein (DBP) is a protein in your blood that binds to vitamin D and other fat-soluble vitamins, helping them travel through your circulatory system. It plays a role in regulating how vitamin D is distributed and utilized by your body’s cells.

Why Might This Test Be Ordered?

Doctors may order this test if they suspect vitamin D deficiency, kidney disease, or other conditions affecting protein levels. It can also be part of broader evaluations for metabolic or endocrine disorders.

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The sample is then processed to measure the concentration of DBP in your serum or plasma.

What Does the Test Result Mean?

Results are not typically interpreted in isolation. They are usually reviewed alongside other lab findings, symptoms, and medical history to assess vitamin D status or related conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated DBP levels may indicate conditions like nephrotic syndrome (kidney disease) or certain genetic disorders. Low levels could be associated with vitamin D deficiency or other metabolic issues, though DBP itself is not the primary indicator of vitamin D status. This test supports a broader understanding of vitamin metabolism and potential systemic health concerns.

Short name

DBP Level

Frequently asked questions

What causes abnormal DBP levels?
Abnormal DBP levels can result from kidney disease, liver disease, or genetic conditions affecting protein synthesis. Vitamin D status, hydration status, and certain medications may also influence results.
Your doctor will determine the frequency based on your health needs, symptoms, or risk factors. Routine screening for DBP alone is not standard unless part of a broader evaluation.
Dietary factors like protein intake or certain medications (e.g., steroids) may indirectly influence protein levels, but DBP itself is not directly affected by vitamin D supplements unless there is a known genetic or metabolic condition.
Is this test painful?
The blood draw itself may cause mild discomfort, but most people experience only a brief pinch. Recovery is usually quick, and most people can return to normal activities immediately.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy