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Vitamin B12 (Serum Concentration) – Confirmatory Test

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of vitamin B12 (also called cobalamin) in your blood to check if your body has enough of this essential nutrient.

Quick summary

["Vitamin B12 helps keep your nerves and blood cells healthy and is crucial for energy and brain function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
55884-1
Short code
Vit B12b Ur-sCnc
Synonyms
Vit B12b Ur-sCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
200
Ref high
900
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, numbness, tingling in the hands or feet, dizziness, or memory problems. It could also be done if you have conditions like pernicious anemia, certain dietary restrictions (e.g., veganism), or if prior tests suggested low vitamin B12 levels.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm, and a few drops of blood will be collected into a tube. The process usually takes a few minutes and is generally painless.

What the Results Mean

Results are compared to a reference range for healthy adults. Low levels may indicate vitamin B12 deficiency, which can be caused by poor diet, absorption issues, or certain medical conditions. High levels may require further investigation to rule out other factors.

Common Causes of Low Vitamin B12 Levels

Deficiency can result from dietary lack (e.g., not eating enough meat, fish, or dairy), conditions that interfere with absorption (like atrophic gastritis or pernicious anemia), or medications that reduce vitamin B12 absorption.

Reference range

NCBI: Vitamin B12 200-900 pg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin B12 (Confirm)

Frequently asked questions

What causes vitamin B12 deficiency?
Vitamin B12 deficiency can be caused by poor diet, conditions that affect how your body absorbs nutrients (like stomach or intestinal disorders), certain medications, or health conditions such as pernicious anemia.
How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on your lab and healthcare provider’s workflow. Your doctor will discuss the findings with you during your follow-up visit.
Can I take vitamin B12 supplements before the test?
It’s best to avoid taking vitamin B12 supplements or multivitamins containing B12 for at least a few days before the test, as this could affect the accuracy of the results. Always follow your healthcare provider’s specific instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy