Vitamin B12 (Serum or Plasma Concentration)
This test measures the amount of vitamin B12, a crucial nutrient needed for healthy nerve function and red blood cell production, in your blood.
["Assesses vitamin B12 deficiency, which can affect energy levels and nerve health."]
Key facts at a glance
- LOINC
- 96808-1
- Short code
- Vit B1 IgE Qn
- Synonyms
- Vit B1 IgE Qn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Vitamin B12 is essential for preventing anemia, maintaining nerve function, and supporting DNA synthesis. Low levels may indicate poor absorption, dietary deficiencies, or underlying health conditions.
What to Expect During the Test
A blood sample is drawn from a vein, usually in your arm. The test is quick and typically done in a lab setting. You may feel slight discomfort, but it usually doesn’t require special preparation.
Low vitamin B12 levels can result from dietary insufficiency, conditions like pernicious anemia, or malabsorption issues. High levels are less common but may occur with certain medications or genetic disorders.
Symptoms may include fatigue, weakness, numbness or tingling in hands/feet, balance problems, or memory issues. Some people have no symptoms until deficiency is severe.
Results are compared to a reference range provided by your healthcare provider. While ranges vary by lab, low values may trigger further testing or dietary adjustments.
If your results are low, your doctor may recommend dietary changes, vitamin supplements, or additional tests to identify the cause. High levels may require further evaluation to rule out rare conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Vitamin B12 Level
Frequently asked questions
How often should I get this test?
What can I do to support healthy vitamin B12 levels?
Does stress or diet affect vitamin B12 levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy