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Vitamin B5 (Pantothenic Acid) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin B5 (also called pantothenic acid) in your blood serum. Vitamin B5 is an essential water-soluble vitamin that plays a key role in energy production and maintaining healthy nerve and skin function.

Quick summary

["Check your vitamin B5 levels if you suspect deficiencies or have symptoms linked to low vitamin B5."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81068-9
Short code
Vit B5 24h Est
Synonyms
Vit B5 24h Est
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
estimated
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms such as fatigue, muscle weakness, numbness, or skin problems that might indicate a vitamin deficiency. It may also be part of a broader evaluation for metabolic disorders or nutritional assessment.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a certain period before the blood draw, but this depends on your healthcare provider’s instructions. Bring any medications you’re taking to your appointment.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis. The test typically takes a few minutes, and you may feel slight discomfort but no lasting effects.

What Are the Possible Results?

Results will be reported as a concentration of vitamin B5 in your serum. While reference ranges can vary by lab, low levels may suggest a deficiency, while very high levels could indicate certain medical conditions or medication use.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low vitamin B5 levels can contribute to fatigue, nerve issues, or digestive problems. Severe deficiencies are rare but may occur in individuals with malabsorption disorders, chronic illnesses, or those on certain medications. High levels may require further investigation to rule out underlying conditions like liver disease or certain metabolic disorders.

Short name

Vitamin B5 Level

Frequently asked questions

What causes low vitamin B5 levels?
Low vitamin B5 levels can result from poor diet, digestive disorders that impair absorption, certain medications, or chronic health conditions. Lifestyle factors, such as excessive alcohol use or stress, may also play a role.
How is vitamin B5 deficiency treated?
Treatment typically involves dietary changes to include foods rich in vitamin B5, such as whole grains, legumes, and animal products. Supplements may be recommended under medical supervision if deficiency is confirmed.
Can vitamin B5 levels be affected by medications?
Yes, some medications—like antibiotics, diuretics, or anticonvulsants—may interfere with vitamin B5 absorption or metabolism, potentially leading to low levels. Always discuss medications with your doctor before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy