Pyridoxal phosphate (PLP) and pyridoxine metabolites in serum/plasma
This test measures levels of active forms of vitamin B6 (pyridoxal phosphate) and related metabolites in your blood, helping assess vitamin B6 status and its role in metabolism.
["Vitamin B6 is essential for nerve function, red blood cell production, and metabolism of amino acids and neurotransmitters."]
Key facts at a glance
- LOINC
- 95266-3
- Short code
- Vit B6 + metabolites Pnl SerPl
- Synonyms
- Vit B6 + metabolites Pnl SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like nerve pain, anemia, depression, or unusual fatigue, or if you have conditions such as alcoholism, pregnancy, or certain medications that affect vitamin B6 levels. It may also be used to monitor vitamin B6 status in patients with chronic illnesses or malabsorption disorders.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw. Wear comfortable clothing and plan to rest after the test. Avoid smoking or consuming alcohol for 24 hours before the procedure.
What Happens During the Test
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis using advanced techniques to measure vitamin B6 metabolites.
What the Results Mean
Results help determine if your body has enough vitamin B6 to function properly. Low levels might indicate deficiencies or poor absorption, while high levels could suggest certain metabolic conditions or medication use. Your provider will discuss these results with you in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Vitamin B6 Metabolites (Serum/Plasma)
Frequently asked questions
How long will I need to wait for my results?
What does it mean if my vitamin B6 levels are low?
Can I take vitamin B6 supplements without checking my levels first?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy