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Vitamin C (Ascorbic Acid) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin C, an essential nutrient that helps protect cells from damage and supports immune function.

Quick summary

["Vitamin C helps your body fight infections and maintain healthy skin and tissues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54350-4
Short code
Vit C+DHA SerPl-sCnc
Synonyms
Vit C+DHA SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of vitamin C deficiency, such as fatigue, frequent infections, or slow wound healing. It could also be used to monitor vitamin C levels in people taking supplements or those with certain medical conditions that affect nutrient absorption.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the blood draw, but this depends on your provider’s instructions. Bring any supplements or medications you’re taking to discuss with your doctor.

How the Test Works

A small sample of blood is drawn from a vein in your arm. The sample is then sent to a lab to measure vitamin C levels using a specialized immunoassay method, which detects the presence of vitamin C in your serum or plasma.

What the Results Mean

Results may indicate whether your vitamin C levels are within a normal range, lower than expected (deficiency), or higher than expected (elevated). Your doctor will interpret the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low vitamin C levels can weaken your immune system, increase the risk of infections, and slow healing. High levels may not always cause symptoms but can sometimes indicate over-supplementation or certain medical conditions. Regular monitoring is important for people with chronic illnesses or those on long-term vitamin C therapy.

Short name

Vitamin C Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will contact you once they are ready to discuss your results.
Can I take vitamin C supplements before the test?
If your doctor has instructed you to stop taking vitamin C supplements, do so for at least 24 hours before the test to get an accurate reading. Always follow your provider’s specific instructions.
What are the common symptoms of vitamin C deficiency?
Symptoms may include fatigue, frequent infections, gum bleeding, slow wound healing, joint pain, or skin problems. Severe deficiency can lead to scurvy, which affects skin, bones, and blood vessels. If you experience these symptoms, talk to your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy