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Vitamin D Binding Protein (DBP) – Serum

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of Vitamin D Binding Protein (DBP) in your blood. DBP helps transport vitamin D in your body, but it can also influence how other substances interact with vitamin D metabolism.

Quick summary

["DBP levels may affect how vitamin D is processed and could be relevant in certain health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
61541-9
Short code
Vit D alone PhenX
Synonyms
Vit D alone PhenX
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
30
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
phenx
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Vitamin D Binding Protein (DBP) is a protein in your blood that binds to vitamin D and transports it throughout your body. While its primary role is related to vitamin D, it can also play a role in how other proteins interact with vitamin D’s effects. This test helps assess your body’s ability to handle vitamin D and may be part of broader evaluations for vitamin D deficiency or related metabolic processes.

Why Might This Test Be Ordered?

Doctors may order this test if you have symptoms or conditions linked to vitamin D metabolism, such as unexplained fatigue, bone pain, or if you have a history of vitamin D-related disorders. It may also be part of a broader panel to monitor protein interactions or kidney function, as DBP is produced in the liver and kidneys.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is then processed in a lab to measure the concentration of Vitamin D Binding Protein. No special preparation is usually needed, but you may be asked to fast for a few hours before the test if instructed by your healthcare provider.

What Are Possible Results?

Results are typically reported as a concentration level of DBP in the blood. While reference ranges can vary by lab, they are often used to compare your level to what is expected in healthy individuals. Abnormal results may prompt further testing or evaluation of underlying conditions.

Reference range

NCBI: Vitamin D 30-100 ng/mL (sufficient)N/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated levels of DBP might suggest conditions affecting liver or kidney function, as these organs produce or process DBP. Low levels could be associated with certain genetic disorders or metabolic issues. Since DBP interacts with vitamin D, abnormal levels may indirectly influence vitamin D metabolism, potentially affecting bone health or other vitamin D-dependent processes. Always discuss results with your healthcare provider for personalized interpretation.

Short name

DBP Serum

Frequently asked questions

What does a Vitamin D Binding Protein test measure?
This test measures the concentration of Vitamin D Binding Protein (DBP) in your blood serum. DBP is a protein that helps transport vitamin D and may influence how other substances interact with vitamin D’s effects in your body.
Can I eat or drink before this test?
Generally, no special dietary restrictions apply unless your healthcare provider specifies otherwise. Follow their instructions if they recommend fasting or avoiding certain foods/drinks before the test.
What conditions might affect Vitamin D Binding Protein levels?
Conditions affecting liver or kidney function, certain genetic disorders, or metabolic issues could influence DBP levels. Your doctor may also consider other factors like vitamin D status or medications you’re taking when interpreting results.
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Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy