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24-Hour Urine Intake of a Specific Substance (e.g., Sodium, Potassium, or Water)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a substance your body excretes in urine over a full day. It helps doctors assess how much of a particular substance (like minerals, water, or other chemicals) your kidneys filter and remove from your blood.

Quick summary

["Helps track kidney function and fluid balance by measuring daily excretion of specific substances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81077-0
Short code
Vit E intake 24h Measured
Synonyms
Vit E intake 24h Measured
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
20
Ref high
400
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
measured
CPT
82670
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test typically involves collecting all urine produced in a 24-hour period. The collected urine is then analyzed to determine the total amount of the measured substance. This helps identify patterns in how your body processes and eliminates substances.

Why It’s Done

Doctors may order this test to evaluate kidney function, diagnose conditions like kidney disease, or check for imbalances in electrolytes (such as sodium, potassium), water retention, or metabolic issues.

Sample Collection and Preparation

You’ll need to collect every drop of urine for 24 consecutive hours, starting and ending at the same time each day. Store the urine in a clean container and keep it refrigerated until you return it to the lab. Proper collection ensures accurate results.

Common Conditions Monitored

This test is often used to monitor conditions like hypertension (high blood pressure), kidney disease, heart failure, or metabolic disorders. It can also help assess how well your body handles fluids and electrolytes.

Reference range

Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: This test provides critical insights into kidney function and fluid balance. Abnormal results may indicate kidney damage, electrolyte imbalances, or other systemic health issues that require medical attention.

Short name

24h Urine Measurement

Frequently asked questions

Why is my doctor asking for this test?
Your doctor may recommend it to check if your kidneys are working properly, to diagnose or monitor conditions affecting fluid balance, or to evaluate how your body processes certain substances.
What does a high or low result mean?
High levels may suggest kidney problems, overhydration, or certain medications affecting excretion. Low levels could indicate kidney dysfunction, dehydration, or conditions like Addison’s disease.
How long will I need to prepare for this test?
You’ll need to collect urine for 24 hours straight, so plan accordingly. Follow your doctor’s instructions for timing and storage to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy