Vitronectin in Plasma (Mass Concentration)
This test measures the amount of vitronectin, a protein produced by the liver that helps regulate blood clotting and supports the stability of blood vessels.
["Vitronectin helps maintain healthy blood flow and vessel integrity; abnormal levels may signal liver disease or other conditions."]
Key facts at a glance
- LOINC
- 3130-2
- Short code
- Vitronectin Plas-mCnc
- Synonyms
- Vitronectin Plas-mCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms like easy bruising, prolonged bleeding, or signs of liver problems (e.g., jaundice, fatigue). It can also be part of evaluating conditions affecting blood clotting or protein synthesis in the liver.
What Does the Test Involve?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate plasma, where vitronectin is measured using a specialized laboratory technique.
Sample Collection and Processing
The test uses plasma, the liquid part of blood that contains proteins like vitronectin. This is typically obtained after centrifugation to remove cells, ensuring accurate measurement of the protein concentration.
What Might Abnormal Results Mean?
Low levels of vitronectin may indicate liver disease (e.g., cirrhosis), protein-losing syndromes, or certain genetic disorders affecting blood clotting. High levels are less common but could relate to acute-phase responses or rare metabolic conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Vitronectin plays a role in fibrinolysis (the breakdown of blood clots) and vascular stability. Reduced levels can impair clot resolution or vessel integrity, while elevated levels may suggest inflammation or metabolic stress. This test is particularly useful in diagnosing or monitoring conditions affecting liver function or protein synthesis.
Short name
Vitronectin Level
Frequently asked questions
How is this test different from other protein tests?
What are typical reference ranges?
Can diet or medications affect vitronectin levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy