Vitamin K-dependent clotting factors (serum/plasma) profile
This test measures several blood proteins that help your blood clot normally when you’re injured. Vitamin K is needed for their production.
["Assesses blood clotting function with key proteins that require Vitamin K for proper function."]
Key facts at a glance
- LOINC
- 75101-6
- Short code
- VLCFA C22:0 EntSub RBC
- Synonyms
- VLCFA C22:0 EntSub RBC
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Your blood sample will be tested for multiple clotting factors that rely on Vitamin K for their activity. These include factors II (prothrombin), VII, IX, and X, as well as protein C and protein S. The results help evaluate how well these proteins function in your blood.
Why It’s Ordered
Doctors may order this test if you have bleeding problems, clotting issues, or if you’re taking medications that affect blood clotting (like warfarin). It can also help diagnose conditions like vitamin K deficiency or liver disease that may affect clotting.
Common Conditions Monitored
This test is often used to monitor patients on anticoagulant therapy to ensure their medication levels are safe and effective. It can also identify problems with Vitamin K absorption or liver function that might interfere with normal clotting.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is collected into a special tube that separates serum or plasma from cells. This sample is then sent to a lab for testing.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Vitamin K Factors Profile
Frequently asked questions
How long will it take to get my results?
What do my results mean?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy