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Fibrinogen concentration (serum/plasma mass concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps with clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports overall blood health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74615-6
Short code
VLCFA C22:0 Fib-mCnt
Synonyms
VLCFA C22:0 Fib-mCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Fibrinogen?

Fibrinogen is a key protein in your blood that plays a vital role in preventing excessive bleeding and promoting proper clotting. It’s produced by your liver and helps form clots when needed. Low or high levels can affect how your blood clots and may signal underlying health concerns.

Why Might You Need This Test?

Your doctor may order a fibrinogen test to check for bleeding disorders, clotting problems, or conditions like liver disease, kidney disease, or certain cancers. It can also help monitor treatments for conditions like disseminated intravascular coagulation (DIC) or after surgeries or injuries.

How Is the Test Done?

A small blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab to measure fibrinogen levels. The test is quick and typically done as part of a routine blood draw.

What Does the Result Mean?

Results are usually reported as a numerical value (mass concentration) but aren’t always compared to a standard range unless specified by your doctor. Low fibrinogen may indicate bleeding risks or liver/kidney issues, while very high levels could signal clotting disorders or inflammation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fibrinogen

Frequently asked questions

What causes abnormal fibrinogen levels?
Abnormal fibrinogen levels can be caused by conditions like liver disease (which affects protein production), kidney problems, infections, inflammation, or certain medications. It may also be affected by pregnancy, blood clotting disorders, or trauma.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, or treatment plan. Routine blood tests often include fibrinogen as part of a full coagulation panel.
Can lifestyle changes affect fibrinogen?
Yes, diet and activity can influence fibrinogen. Eating a balanced diet rich in vitamins (like vitamin K) and avoiding excessive alcohol may support normal levels, but results depend on overall health and medical conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy