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Fibrinogen (Serum) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen in your blood serum. Fibrinogen is a protein that plays a key role in blood clotting.

Quick summary

["Fibrinogen helps your blood clot when you have an injury, preventing excessive bleeding."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74583-6
Short code
VLCFA C24:0/C22:0 Fib
Synonyms
VLCFA C24:0/C22:0 Fib
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Done

Your healthcare provider may order this test to check for blood clotting problems, such as bleeding disorders or clotting disorders. It can also help evaluate liver function, since the liver produces fibrinogen. Sometimes, it’s used to monitor conditions like kidney disease or certain cancers.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel, but this depends on your provider’s instructions. Bring any medications you’re taking to your appointment.

How the Test Is Performed

A blood sample is drawn from a vein in your arm, typically by a phlebotomist. The blood is sent to a lab where it’s analyzed to measure fibrinogen levels using a specialized method, often turbidimetry or nephelometry.

What the Results Mean

Results are reported in milligrams per deciliter (mg/dL) or grams per liter (g/L). Low levels may suggest liver disease, clotting disorders, or severe infections. High levels could indicate inflammation, pregnancy, or certain blood disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fibrinogen

Frequently asked questions

Low fibrinogen levels can indicate liver disease (like cirrhosis), severe infections, or blood clotting disorders. High levels may be linked to inflammation, pregnancy, or certain cancers. Monitoring fibrinogen helps diagnose and manage conditions affecting blood clotting or liver function.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
Most often, no fasting is required unless your provider specifies otherwise. Always follow their instructions to avoid delays or inaccurate results.
You may experience mild bruising or soreness at the injection site, which usually goes away quickly. Apply gentle pressure to the area for a few minutes after the draw. Avoid heavy lifting or strenuous activity for a short time if instructed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy