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Vitamin D Binding Protein (DBP) with Serum/Plasma Concentration Measurement

Published: August 9, 2026Updated: August 17, 2026

This test measures the concentration of Vitamin D Binding Protein (DBP) in your blood. DBP helps transport vitamin D and other fat-soluble hormones in your body.

Quick summary

["DBP levels can provide insight into vitamin D metabolism and its role in hormone transport."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
75105-7
Short code
VLCFA C26:1 EntSub RBC
Synonyms
VLCFA C26:1 EntSub RBC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions related to vitamin D metabolism, such as unexplained fatigue, bone pain, or if you have a history of kidney disease or certain genetic disorders. It could also be part of a broader evaluation for conditions affecting hormone function or mineral balance.

What to Expect Before the Test

No special preparation is typically needed. You may have a blood sample drawn from a vein in your arm, similar to other routine blood tests. If you’re on blood thinners, let your provider know before the test.

What the Test Results Mean

Results show the amount of DBP in your blood. While reference ranges can vary by lab, abnormal levels may suggest issues like kidney disease, genetic disorders (e.g., vitamin D-resistant rickets), or other metabolic conditions. Your provider will interpret results in the context of your overall health.

Common Conditions Linked to DBP Levels

High DBP levels might be linked to kidney disease or certain genetic disorders affecting hormone transport. Low levels could indicate conditions where vitamin D metabolism is disrupted, though this is less common. Always discuss results with your provider.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: DBP’s Role in Health

Short name

Vitamin D Binding Protein (DBP) Level

Frequently asked questions

How is DBP measured in this test?
This test uses an immunoassay method (likely nephelometry or turbidimetry) to detect and quantify DBP in your serum or plasma. The method identifies the protein’s presence by measuring how it interacts with specific antibodies or particles.
What if my DBP level is outside the normal range?
If your results are outside the expected range, your provider may order additional tests (e.g., vitamin D levels, kidney function tests) to explore underlying causes. For example, low DBP could hint at kidney issues, while high levels may warrant further evaluation for metabolic disorders.
Can diet or supplements affect DBP levels?
Dietary factors like vitamin D intake or protein-rich foods may indirectly influence DBP levels, but DBP itself is not directly affected by supplements. If you’re taking medications (e.g., steroids), let your provider know—some drugs can alter protein levels in the blood.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy