Vitamin K-dependent clotting factors (Serum Protein Electrophoresis with Factor Analysis)
This test measures specific blood proteins involved in clotting, often checked if you have bleeding issues or clotting disorders.
["Helps assess blood clotting function by evaluating key proteins made possible by vitamin K."]
Key facts at a glance
- LOINC
- 33036-5
- Short code
- VLCFA C26:1 SerPl-sCnc
- Synonyms
- VLCFA C26:1 SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
This test evaluates the concentration of vitamin K-dependent clotting factors in your serum. These factors (such as factors II, VII, IX, and X) are essential for normal blood clotting. The test may also include a protein electrophoresis component to analyze overall serum protein composition, though the specific factors are highlighted here.
Why It’s Ordered
Your healthcare provider may order this test if you have symptoms like excessive bleeding, easy bruising, or prolonged bleeding after procedures. It’s also used to monitor conditions like vitamin K deficiency, liver disease, or certain medications that affect clotting.
Sample Preparation
A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum (the liquid part after clotting) for testing. Avoid alcohol or aspirin for 24 hours before the test, as they may affect clotting factors.
What to Expect
The test is quick and usually done in a lab setting. You may feel a slight pinch when the needle is inserted, but it’s over quickly. Results are typically ready within a few days, depending on lab processing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Vitamin K Factors (Serum Electrophoresis)
Frequently asked questions
Low levels of these clotting factors may indicate vitamin K deficiency, liver disease, or certain medications disrupting clotting. High levels could be seen in rare genetic conditions or overproduction of proteins. Monitoring helps manage bleeding disorders or prevent excessive clotting risks.
Results are usually available within 2 to 5 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
Yes, dietary sources of vitamin K (like leafy greens, broccoli, and some oils) can influence clotting factor levels. Avoid high-fat foods 24 hours before the test if your provider recommends it.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy