Skip to content

VLDL Cholesterol, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of VLDL cholesterol in blood. VLDL is a cholesterol-carrying particle that transports triglycerides from the liver to other tissues.

Quick summary

["VLDL cholesterol is one part of your lipid profile and is interpreted along with triglycerides, HDL cholesterol, and other cardiovascular risk factors."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50192-4
Short code
VLDL1+2+3c SerPl-mCnc
Synonyms
VLDL1+2+3c SerPl-mCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of VLDL cholesterol in serum or plasma, which is the liquid portion of your blood. VLDL is made mainly by the liver and carries triglycerides and other lipids throughout the body.

Why might I need this test?

VLDL cholesterol is usually included as part of a broader lipid profile. Your clinician may use it to assess cholesterol-related cardiovascular risk or to evaluate and monitor conditions involving elevated triglycerides and abnormal lipid levels.

How is the test performed?

A blood sample is collected and analyzed in a laboratory. Depending on the laboratory, VLDL cholesterol may be measured directly or calculated from other results in the lipid panel, including total cholesterol, HDL cholesterol, and triglycerides.

How do I prepare for the test?

Follow your clinician's instructions about fasting, because eating before the test can raise triglycerides and affect the lipid profile. If no specific instructions were given, ask whether you should fast. You may continue medications unless your clinician tells you otherwise.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Higher VLDL cholesterol may be associated with elevated triglycerides, insulin resistance, obesity, and increased cardiovascular risk, although it is interpreted as part of the complete lipid profile. VLDL cholesterol is not usually assessed independently, and its meaning depends on other laboratory results and personal risk factors. Your clinician can explain how this result relates to your overall health.

Short name

VLDL Cholesterol

Frequently asked questions

Is VLDL cholesterol the same as LDL cholesterol?
No. They are different types of cholesterol-carrying particles. VLDL mainly carries triglycerides from the liver, while LDL primarily transports cholesterol to tissues and is often evaluated separately for cardiovascular risk.
Does VLDL cholesterol need to be measured directly?
Not always. Some laboratories calculate VLDL cholesterol from other values in the lipid panel, while others use a direct measurement. The laboratory report should indicate how the result was obtained.
Do I need to fast for this test?
Fasting may be recommended, especially when triglycerides are being evaluated, because a recent meal can change lipid results. Follow the instructions provided by your clinician or testing laboratory.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy