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VLDL Subclass 3 Cholesterol, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of cholesterol carried by the VLDL subclass 3 lipoprotein particles in a blood sample.

Quick summary

["This test helps assess a specific component of cholesterol transport and may be used alongside a complete lipid profile."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46986-6
Short code
VLDL3c SerPl-mCnc
Synonyms
VLDL3c SerPl-mCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Very-low-density lipoprotein (VLDL) is made in the liver and helps transport triglycerides and cholesterol through the blood. This test measures the mass concentration of cholesterol in the VLDL subclass 3 particles, sometimes called VLDL-3 cholesterol.

Why might I need this test?

VLDL-3 cholesterol may be ordered when a clinician is evaluating cholesterol transport, lipid metabolism, or cardiovascular risk. It is usually interpreted with total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, and other lipid measurements.

How is the test performed?

A serum or plasma blood sample is analyzed in the laboratory to determine the concentration of VLDL-3 cholesterol. The specific laboratory method is not identified in the submitted test code.

How do I prepare for the test?

Follow the preparation instructions provided by your clinician or laboratory. Fasting may be requested for some lipid tests, and you should not fast for an extended period unless specifically instructed to do so.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

VLDL-3 cholesterol

Frequently asked questions

Is VLDL-3 cholesterol the same as total VLDL cholesterol?
No. VLDL-3 cholesterol measures cholesterol within a specific VLDL subclass, whereas total VLDL cholesterol includes cholesterol carried by all VLDL particles.
Does this test require fasting?
It depends on the order and the laboratory's instructions. Fasting may be recommended when the test is part of a broader lipid evaluation.
What does an abnormal result mean?
It may reflect an imbalance in cholesterol or triglyceride transport, but the result must be considered alongside other lipid measurements and your overall health. Your clinician can explain the meaning of your specific result.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy