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VLDL Cholesterol, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures very-low-density lipoprotein cholesterol in serum or plasma, usually as part of a lipid assessment.

Quick summary

["This test measures the cholesterol carried by VLDL particles and is generally interpreted with your other lipid results."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35199-9
Short code
VLDLc SerPl-msCnc
Synonyms
VLDLc SerPl-msCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

VLDL cholesterol is the amount of cholesterol carried by very-low-density lipoprotein particles in your blood. VLDL is produced by the liver and helps transport triglycerides to other tissues.

Why might I need this test?

This test may be included in a lipid panel or ordered to assess cholesterol levels, especially when triglycerides are elevated or cardiovascular risk is being evaluated. It is usually interpreted along with total, LDL, and HDL cholesterol rather than by itself.

How is the test performed?

A blood sample is collected, and the amount of cholesterol in the VLDL fraction is measured in the laboratory. The result is reported as a mass concentration in the sample.

How do I prepare for the test?

Follow any fasting or timing instructions provided by your clinician or laboratory. Fasting may be requested when this test is part of a complete lipid panel, but do not fast unnecessarily unless instructed.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated VLDL cholesterol result may occur with high triglyceride levels, obesity, diabetes, or other conditions that affect lipid metabolism. It can contribute to the overall cardiovascular risk pattern, so results should be reviewed with the other lipid measurements and your medical history.

Short name

VLDL Cholesterol

Frequently asked questions

Is VLDL cholesterol the same as LDL cholesterol?
No. VLDL and LDL are different types of cholesterol-carrying particles. VLDL mainly carries triglycerides, while LDL mainly carries cholesterol.
Does a high VLDL cholesterol result mean I have heart disease?
No. This result alone does not diagnose heart disease. It is interpreted with your total, LDL, and HDL cholesterol, triglycerides, and other risk factors.
How often should VLDL cholesterol be checked?
The frequency depends on your health history, risk factors, and the reason the test was ordered. Your clinician can recommend a schedule based on your overall lipid profile.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy