VLDL Lipoprotein Subfraction Analysis (Serum or Plasma Mass Concentration)
This test measures different types of very low-density lipoprotein (VLDL) particles in your blood, which carry fats (lipids) to your body’s cells. It helps assess how your liver produces and distributes these fats.
["Understanding your VLDL levels can help identify risks for heart disease or metabolic conditions."]
Key facts at a glance
- LOINC
- 43728-5
- Short code
- VLDL large SerPl-sCnc
- Synonyms
- VLDL large SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 100
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83721
- SNOMED
- 113079007
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of high cholesterol, a family history of heart disease, or conditions like diabetes or obesity. It can also be part of routine cardiovascular risk assessments.
What to Expect Before the Test
You’ll typically fast for 12 hours before the test to get an accurate reading. Avoid smoking, caffeine, and alcohol for at least a few hours beforehand. Bring any medications you’re currently taking to your appointment.
How the Test Works
A blood sample is drawn from a vein in your arm. The lab then separates your blood into its components, including VLDL particles, to measure their mass concentration. This process helps identify specific VLDL subfractions.
What the Results Mean
Results provide detailed information about the size, number, and fat content of VLDL particles. High levels of certain VLDL types may indicate increased risk for atherosclerosis or other cardiovascular issues.
Reference range
Optimal: <100 mg/dLN/A
Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
High levels of certain VLDL subfractions can contribute to plaque buildup in arteries, increasing the risk of heart disease. This test helps healthcare providers tailor lifestyle or medication recommendations to manage cholesterol and cardiovascular health.
Short name
VLDL Lipoprotein Profile
Frequently asked questions
What does a VLDL lipoprotein profile test measure?
How long does it take to get results from this test?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy