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Serum Creatinine Concentration (Mass Concentration) via Enzymatic Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function by checking how well your kidneys filter blood.

Quick summary

["A creatinine test helps evaluate kidney health and filter function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108300-5
Short code
VMA/Creatine Msmt Ur
Synonyms
VMA/Creatine Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. If your kidneys aren’t working well, creatinine levels in your blood can rise. This test is a key part of checking for kidney disease or damage.

How the Test Works

A small blood sample is taken from your arm and sent to a lab. There, enzymes detect the creatinine levels in your serum. The result tells your healthcare provider how well your kidneys are working.

What to Expect Before the Test

You may have no special preparation needed, but let your doctor know if you’re taking certain medications or have conditions like diabetes or heart disease. Avoid strenuous activity before the test.

Possible Results and Next Steps

Results may be compared to a reference range (if provided) to see if your levels are normal or if further testing is needed. High levels might indicate kidney problems, while very low levels could suggest muscle disorders or errors in testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level (Serum)

Frequently asked questions

What does a high creatinine level mean?
What does a low creatinine level mean?
Low creatinine levels may suggest muscle atrophy, malnutrition, or errors in lab testing. However, this is less common and usually requires further investigation by your healthcare provider.
Can diet affect creatinine levels?
Dietary changes, such as eating more protein, can temporarily raise creatinine levels. However, your doctor will consider overall health and other factors when interpreting results.
Your doctor may recommend this test periodically if you have a history of kidney issues, diabetes, or high blood pressure. Regular monitoring helps track kidney function over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy