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Vitamin D binding protein (DBP) or Vitamin D-binding protein (VDBP) mass concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a protein in your blood that helps transport vitamin D. It can be part of a broader evaluation for vitamin D metabolism or related conditions.

Quick summary

["This test helps assess how your body may handle vitamin D."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20351-3
Short code
Vmax DOP
Synonyms
Vmax DOP
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-doppler
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to vitamin D metabolism, such as unexplained fatigue, bone pain, or certain genetic disorders. It may also be used in research or specialized clinical settings to evaluate protein levels indirectly tied to vitamin D transport.

What to Expect Before the Test

No special preparation is typically needed. You may have a simple blood draw from a vein in your arm. If you’re taking blood thinners or have a history of bleeding disorders, let your provider know.

What the Test Results Mean

Results are usually reported as a mass concentration (e.g., grams per liter). While reference ranges vary by lab, abnormal levels might suggest conditions affecting protein synthesis, kidney function, or vitamin D metabolism. Your provider will interpret results in the context of your overall health.

Common Conditions Linked to This Test

While vitamin D-binding protein itself isn’t directly linked to many common diseases, its levels can be studied in conditions like hereditary vitamin D-resistant rickets or other metabolic disorders. It may also be monitored in research or specialized cases where vitamin D transport is under investigation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin D-binding protein level

Frequently asked questions

What causes vitamin D-binding protein levels to change?
Changes in vitamin D-binding protein levels can result from genetic factors (e.g., hereditary conditions), kidney disease, liver disease, or certain medications. It may also fluctuate due to overall protein metabolism in the body.
Can this test help diagnose vitamin D deficiency?
No, this test alone does not diagnose vitamin D deficiency. It measures a protein involved in vitamin D transport and may be used alongside other tests (like vitamin D levels) to assess metabolic pathways.
How often should I get this test?
The frequency depends on your healthcare needs. Your provider will determine if and how often this test is needed based on your symptoms, medical history, or specific clinical reasons.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy