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Mean corpuscular volume (MCV) of red blood cells

Published: August 9, 2026Updated: August 16, 2026

This test measures the average size of your red blood cells (RBCs) to help diagnose conditions affecting blood production or shape.

Quick summary

["MCV helps identify whether your blood may need further evaluation for anemia or other blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33878-0
Short code
Vmean US
Synonyms
Vmean US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is MCV Used For?

MCV is commonly used to classify types of anemia. Low MCV may suggest conditions like iron deficiency or thalassemia, while high MCV could indicate alcohol use, vitamin deficiencies (such as folate or B12), or certain liver diseases.

How Is MCV Tested?

This test is performed on a small sample of your blood drawn from a vein. The lab measures the size of your red blood cells using automated technology.

What Does an MCV Result Mean?

Results are not given in absolute numbers but are compared to standard ranges. Abnormal values may prompt additional tests to uncover underlying causes.

Common Conditions Linked to MCV Changes

Low MCV is often linked to microcytic anemia, while high MCV may signal macrocytic anemia. These findings can guide further medical evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

MCV

Frequently asked questions

Why might my doctor order an MCV test?
Your doctor may recommend an MCV test if you have symptoms like fatigue, pale skin, or unexplained weakness, or if they suspect anemia or other blood-related issues.
What are typical reference ranges for MCV?
Reference ranges vary by lab but generally fall between 80 and 100 femtoliters (fL) for adult males and females. Exact values may differ by lab.
Can lifestyle changes affect MCV results?
Yes, diet (especially iron, vitamin B12, and folate intake), alcohol consumption, and certain medications can influence MCV levels. Discuss any changes with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy