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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function by checking how well your kidneys filter blood.

Quick summary

["A creatinine test helps doctors evaluate kidney health and diagnose kidney disease early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15319-7
Short code
Volume Testis-L by AUT
Synonyms
Volume Testis-L by AUT
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-derived-aut
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out of your blood by your kidneys. If your kidneys aren’t working well, creatinine builds up in your blood. Measuring it helps determine how effectively your kidneys are functioning and can indicate early kidney problems.

How the Test Works

Blood is drawn from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure creatinine levels using a specialized test method. The result is compared to a reference range to assess kidney function.

What to Expect Before the Test

You can eat and drink normally before the test, as creatinine levels don’t change significantly with food or hydration unless you’re being monitored closely for kidney function. Avoid excessive alcohol or contrast dyes (if prescribed) before the test, as they may affect results.

What to Expect During the Test

The test involves a quick blood draw, typically done by a healthcare professional. You may feel a slight pinch, but it usually takes only a few seconds. The blood sample is then processed and sent to the lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

What causes creatinine levels to be high?
High creatinine levels can be caused by kidney disease, dehydration, severe muscle damage, or certain medications. If you notice unexplained fatigue, swelling, or changes in urine output, discuss these symptoms with your doctor.
What should I do if my creatinine level is abnormal?
If your creatinine level is elevated, your doctor may recommend further tests, adjustments to your medications, or lifestyle changes to support kidney health. Follow their guidance closely and attend follow-up appointments.
Can diet affect creatinine levels?
Diet alone typically doesn’t change creatinine levels significantly unless you’re being monitored for kidney function in a controlled setting (e.g., after a kidney transplant or during dialysis). Focus on a balanced diet and stay hydrated unless advised otherwise by your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy