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Lipid profile (total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol) derived from a 24-hour urine collection

Published: August 9, 2026Updated: August 16, 2026

This test measures fat-related substances in your urine over a full day to help assess how your body processes fats and how they may affect your kidneys.

Quick summary

["This test helps detect kidney issues linked to fat metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15312-2
Short code
Volume Testis-L US.derived.ROT
Synonyms
Volume Testis-L US.derived.ROT
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-derived-rot
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like unexplained fatigue, swelling in your legs, or if tests suggest your kidneys aren’t working well. It can also be part of routine checks for people at higher risk of kidney disease, especially those with diabetes, high blood pressure, or a family history of kidney problems.

What to Expect Before the Test

You’ll need to collect all your urine for 24 hours, starting and ending the collection at the same time each day. Drink plenty of water to help your urine flow normally. Avoid certain medications or supplements that might affect fat levels in your urine, as discussed with your doctor.

How the Test Works

Your urine sample is analyzed to measure specific fat-related substances, including cholesterol and triglycerides. These substances are broken down differently in your body, and their presence in urine can reflect how well your kidneys filter them out.

What the Results Mean

High levels of these substances in urine may indicate problems with fat metabolism or kidney function. Your doctor will compare your results with what’s typical for healthy individuals and discuss them with you based on your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How often should I collect urine for this test?
You should collect urine for a full 24-hour period, starting and ending at the same time each day. This ensures your results reflect your typical fat metabolism over a full day. Follow your healthcare provider’s instructions carefully for accurate results.
Can I eat or drink anything before this test?
You can eat a normal diet, but avoid excessive alcohol or high-fat foods that might influence fat levels in your urine. Drink plenty of water to help your urine flow normally. Always check with your doctor or lab technician for specific dietary guidelines.
What if I miss any urine during the collection?
If you miss any urine, your test results may not be accurate. Try to collect all urine as closely as possible to the 24-hour window. If you accidentally miss urine, contact your doctor or lab immediately to reschedule the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy