Serum or Plasma Protein Electrophoresis (Bromocresol Green)
This test measures the different types of proteins in your blood, separated by size and charge, using a dye called bromocresol green. It helps identify abnormalities in protein distribution that may suggest conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors diagnose and monitor protein-related blood disorders."]
Key facts at a glance
- LOINC
- 100907-5
- Short code
- VRE Spec Cult
- Synonyms
- VRE Spec Cult
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- organism-specific-culture
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test to investigate symptoms such as unexplained weight loss, fatigue, swollen lymph nodes, or changes in urine appearance. It’s also used to monitor conditions like multiple myeloma, kidney disease, or liver problems where protein levels or patterns might be affected.
What to Expect Before the Test
No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn in the morning. Wear comfortable clothing and plan to stay near the lab for about 15 minutes while blood is drawn.
What Happens During the Test
A healthcare professional will draw blood from a vein in your arm. The blood sample is then processed and mixed with bromocresol green dye. The sample is applied to a gel and separated into bands representing different protein types, which are then analyzed.
What the Results Mean
Results show the distribution of proteins, including albumin, globulins, and other fractions. Abnormal patterns (e.g., spikes in certain proteins) may indicate conditions like monoclonal gammopathy, infections, or organ dysfunction. Your doctor will interpret results in the context of your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Protein electrophoresis is critical for diagnosing and managing conditions affecting protein synthesis or breakdown. For example, a spike in a specific protein band may signal multiple myeloma, while low albumin levels could point to liver or kidney disease. Early detection helps guide treatment decisions and monitor disease progression.
Short name
Protein Electrophoresis (BCG)
Frequently asked questions
What does a protein electrophoresis test measure?
How long does it take to get protein electrophoresis results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy