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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how much of a specific protein in your blood binds to bromocresol green dye, which can help assess certain liver or kidney function.

Quick summary

["This test evaluates protein binding capacity, often linked to liver or kidney health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78004-9
Short code
VRSA Islt Ql
Synonyms
VRSA Islt Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The bromocresol green (BCG) dye binding test evaluates the concentration of a protein in your blood that binds to this dye. This protein is often related to liver function, as it may reflect the overall protein synthesis capacity of the liver. The test indirectly assesses how well your liver can produce and maintain certain proteins.

Why It’s Done

Doctors may order this test to investigate liver disease, kidney dysfunction, or other conditions affecting protein metabolism. It can also be used in research or specialized clinical settings where protein binding characteristics are important.

Common Uses and Considerations

This test is less commonly performed in routine clinical practice compared to more direct liver function tests (like bilirubin or albumin). It may be used in specific cases where protein binding abnormalities are suspected, such as in chronic liver disease or certain genetic disorders.

What to Expect Before the Test

No special preparation is typically required. You may have a blood sample drawn from a vein, similar to other routine blood tests. If you’re on medications or have certain health conditions, let your healthcare provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Dye Binding Assay

Frequently asked questions

How does this test help doctors?
This test can provide insight into protein synthesis and binding capacity, which may indirectly reflect liver health. Abnormal results could suggest conditions like cirrhosis, liver failure, or other metabolic disorders affecting protein production.
What does a low or high result mean?
A low result might indicate reduced protein synthesis (e.g., liver disease), while a high result could suggest conditions where protein binding is altered (e.g., certain genetic disorders or acute phase reactions). Results should always be interpreted by a healthcare professional in the context of your overall health.
Can this test be combined with other tests?
Yes, this test is often used alongside other liver function tests (like albumin, bilirubin, or ALT) to get a more comprehensive picture of your health. Your doctor will review all results together.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy