Skip to content

Folate (Serum) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of folate, a B vitamin, in your blood. Folate helps your body make healthy red blood cells and DNA.

Quick summary

["Check your folate levels to ensure proper vitamin intake and prevent deficiencies that could affect blood health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68324-3
Short code
vWf:Ac Act/Nor PPP IA
Synonyms
vWf:Ac Act/Nor PPP IA
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like fatigue, weakness, or a sore tongue, or if you have conditions like anemia or pregnancy. It can also help diagnose or monitor folate deficiency.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re pregnant or have a history of bleeding disorders, let your doctor know.

What to Expect During the Test

The blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause pain. The process takes a few minutes.

What the Results Mean

Low levels may indicate a deficiency, which can be caused by poor diet, certain medications, or malabsorption issues. High levels might suggest liver disease or other conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low folate levels can lead to anemia, neurological problems, or increased risk of birth defects in pregnancy. Doctors often recommend folate supplements for pregnant women to prevent neural tube defects in the baby.

Short name

Serum Folate

Frequently asked questions

What causes low folate levels?
Folate deficiency can result from poor diet (low intake of leafy greens, beans, and fortified foods), alcohol use, certain medications (like anticonvulsants), or conditions that affect nutrient absorption (e.g., celiac disease).
How long does it take to correct a folate deficiency?
With dietary changes or supplements, folate levels can improve within weeks to months, depending on the severity. Follow-up tests may be needed to monitor progress.
Can folate levels be affected by stress or diet?
Yes, stress, poor diet, or alcohol consumption can lower folate levels. Eating a balanced diet rich in folate (e.g., spinach, lentils) or taking supplements (if advised) can help maintain healthy levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy