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Vitamin D Binding Protein (DBP) Total Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of vitamin D binding protein in your blood, which helps transport vitamin D and other hormones.

Quick summary

["Understanding your vitamin D binding protein levels can support overall hormone function and health monitoring."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6014-5
Short code
vWF Act/Nor PPP Aggr Rst act
Synonyms
vWF Act/Nor PPP Aggr Rst act
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
aggregometry-ristocetin-cofactor-activity
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect conditions affecting vitamin D metabolism, hormone balance, or kidney function. It can also be part of broader evaluations for genetic disorders or certain metabolic syndromes.

What to Expect Before the Test

No special preparation is typically needed. You may provide a blood sample, often drawn from a vein in your arm. If you’re on a blood thinner, let your provider know before the test.

What the Results Mean

Results provide a measure of your total vitamin D binding protein levels in the blood. While reference ranges vary by lab, abnormal levels may indicate underlying health concerns that need further evaluation.

Common Conditions Monitored

Elevated or low levels of vitamin D binding protein may be linked to conditions like nephrogenic systemic fibrosis, certain genetic disorders, or kidney disease. It’s not a standalone diagnostic test but can support broader assessments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Vitamin D binding protein plays a critical role in transporting vitamin D and other hormones in the blood. Abnormal levels may suggest issues with hormone metabolism, kidney function, or genetic conditions that require further medical evaluation.

Short name

Total DBP

Frequently asked questions

What does a normal range mean for me?
A normal range doesn’t mean your health is perfect—it simply indicates your levels fall within the typical range measured by labs. Your provider will interpret results in the context of your overall health and symptoms.
How often should I get this test?
Your provider will determine how often to repeat this test based on your medical history, symptoms, and other test results. Routine screening isn’t standard unless you have a known condition linked to vitamin D binding protein.
Can diet or supplements affect this test?
Dietary factors like vitamin D intake or certain medications (e.g., steroids) may influence vitamin D binding protein levels, but this test measures total protein concentration rather than vitamin D directly. Always follow your provider’s advice on timing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy