Protein Electrophoresis with Multimeric Plasma Protein Analysis (including PPIB)
This test measures the distribution and composition of proteins in your blood, including specific multimeric forms of proteins like plasma protein complex (PPIB). It helps identify abnormalities in protein levels that may suggest conditions like multiple myeloma, liver disease, or other disorders affecting protein synthesis or breakdown.
["This test helps doctors diagnose and monitor conditions affecting blood protein structure and function."]
Key facts at a glance
- LOINC
- 6013-7
- Short code
- vWF multimers PPP IB
- Synonyms
- vWF multimers PPP IB
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ib
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Protein electrophoresis separates blood proteins based on size and electrical charge, revealing patterns that can indicate whether proteins are fragmented, clumped, or otherwise altered. The test specifically looks at multimeric forms of proteins, including plasma protein complexes (PPIB), which may appear in abnormal quantities in certain diseases.
Why It Matters in Your Health
Abnormal protein patterns can signal underlying health issues, such as protein-losing syndromes, infections, or cancers like multiple myeloma. Detecting these changes early can guide treatment decisions.
Common Conditions Monitored
This test is often used to evaluate conditions like multiple myeloma (a cancer of plasma cells), liver disease (affecting protein synthesis), or hereditary protein disorders. It may also help assess kidney function indirectly by detecting proteinuria (excess protein in urine).
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then analyzed using electrophoresis to separate and identify protein components, including multimeric forms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein Electrophoresis
Frequently asked questions
What does a high or low level of multimeric proteins indicate?
How often should this test be done?
Can diet or lifestyle affect this test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy