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Vitamin D Binding Protein (DBP) – Serum or Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin D binding protein in your blood, which helps transport vitamin D and other hormones. It may be ordered to assess vitamin D metabolism or related conditions.

Quick summary

["This test helps doctors understand how your body processes vitamin D and related substances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4680-5
Short code
vWf:RCo PPP-aCnc
Synonyms
vWf:RCo PPP-aCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or risk factors for conditions involving vitamin D binding protein, such as kidney disease, certain genetic disorders, or if you’re being evaluated for vitamin D metabolism issues. It may also be part of broader testing for hormonal imbalances or metabolic disorders.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for a few hours before the blood draw, but this depends on your provider’s instructions. Avoid strenuous activity or smoking for 30 minutes before the test.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are interpreted by your healthcare provider based on your medical history, symptoms, and other test results. Abnormal levels may indicate conditions affecting vitamin D binding protein function, such as kidney disease or genetic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin D Binding Protein Level

Frequently asked questions

What does a high or low vitamin D binding protein level mean?
High levels may be associated with certain genetic disorders or kidney conditions that alter protein metabolism. Low levels could indicate kidney disease or other metabolic issues affecting protein synthesis or transport.
Can diet or supplements affect this test?
Dietary factors or supplements (like vitamin D) may indirectly influence vitamin D metabolism, but they don’t directly impact the vitamin D binding protein level itself. Follow your provider’s instructions for fasting or dietary restrictions if applicable.
Is this test painful?
The blood draw itself is usually mild discomfort, but most people tolerate it well. If you have a hard time with needles, let your provider know so they can take extra precautions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy