Skip to content

Total Protein (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood serum. Proteins are essential for many bodily functions, including transporting nutrients, maintaining fluid balance, and supporting immune responses.

Quick summary

["Your blood protein levels help assess overall health and detect potential issues like malnutrition or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31694-3
Short code
VZV Ab CSF-aCnc
Synonyms
VZV Ab CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Total protein includes a mix of albumin and globulins. Albumin helps keep fluids in your blood vessels, while globulins support immune function and blood clotting. The test is typically performed on a sample of your blood drawn from a vein.

Why Might You Need This Test?

Your doctor may order this test to check for conditions like malnutrition, kidney disease, liver problems, or infections. It can also help monitor certain treatments or conditions that affect protein levels.

How Is the Test Performed?

A small amount of blood is drawn from a vein in your arm. The blood sample is then sent to a lab where it is analyzed to determine the total protein concentration.

What Are Common Results?

Results are usually reported in grams per deciliter (g/dL). While specific reference ranges can vary by lab, lower than expected levels may suggest malnutrition or liver/kidney disease, while higher levels could indicate dehydration or conditions like multiple myeloma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein levels can signal underlying health issues. Low protein levels may indicate poor nutrient absorption, chronic illness, or organ dysfunction. High protein levels can sometimes reflect dehydration or certain inflammatory conditions. Regular monitoring of protein levels is important for patients with chronic diseases like kidney disease or liver disorders.

Short name

Total Protein

Frequently asked questions

What could cause my protein levels to be low?
Low protein levels can result from conditions like malnutrition, severe infections, kidney disease, liver disease, or certain medications. It may also occur if you’re unable to absorb nutrients properly, such as in cases of gastrointestinal disorders.
What could cause my protein levels to be high?
High protein levels can sometimes be due to dehydration, certain types of cancer (like multiple myeloma), or inflammatory conditions. Rarely, it may also be linked to conditions affecting the immune system or blood clotting.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and any ongoing conditions. Regular check-ups or monitoring may be recommended if you have chronic health issues like kidney or liver disease.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy