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Total Protein in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum, which includes albumin and other proteins like globulins.

Quick summary

["Your blood protein levels help assess overall health and detect conditions like malnutrition or kidney disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9636-2
Short code
VZV Ab CSF Ql
Synonyms
VZV Ab CSF Ql
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Blood proteins play a vital role in maintaining fluid balance, supporting immune function, and transporting nutrients. Abnormal levels may signal underlying health issues, such as chronic kidney disease, liver problems, or malnutrition.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein in your arm to draw blood. If you’re on blood thinners or have a history of bleeding disorders, let your provider know.

What the Results Mean

Higher-than-normal protein levels might indicate conditions like dehydration, multiple myeloma, or severe infections. Lower-than-normal levels could suggest malnutrition, liver disease, or kidney problems. Your doctor will interpret results in the context of your overall health.

Common Conditions Monitored

This test is often used to monitor kidney function, liver health, nutritional status, and immune response. It may also help diagnose conditions like protein-losing gastrointestinal disorders or inflammatory diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Total protein levels can reflect systemic health. For example, low protein levels may indicate poor nutrient absorption or organ dysfunction, while high levels could suggest dehydration or certain cancers. Always discuss results with your healthcare provider.

Short name

Total Protein

Frequently asked questions

What causes abnormal protein levels?
Abnormal protein levels can result from conditions like kidney disease (which may cause protein to leak into urine), liver disease (affecting protein synthesis), malnutrition, infections, or certain cancers. Diet, hydration status, and medications can also influence results.
How often should I get this test?
Your doctor will determine how often to check your protein levels based on your medical history, symptoms, and other tests. Some people may need this test annually or more frequently if they have chronic conditions like kidney disease or liver problems.
Can diet affect protein test results?
Yes, diet can influence protein levels. High-protein diets or certain medical conditions (like kidney disease) may temporarily alter results. Avoid extreme dietary changes before testing, and follow your doctor’s advice for timing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy