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Vitamin D Binding Protein (DBP) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a protein in your blood that helps transport vitamin D. It can be part of a broader evaluation for vitamin D deficiency or related conditions.

Quick summary

["This test helps assess how well your body may be using vitamin D."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31981-4
Short code
VZV Ag Skin Ql
Synonyms
VZV Ag Skin Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms of vitamin D deficiency, such as fatigue, muscle weakness, or bone pain. It may also be used in conjunction with other tests to evaluate vitamin D status, especially in cases where vitamin D levels alone are unclear or if you have certain medical conditions that affect vitamin D metabolism.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Avoid excessive alcohol or certain supplements (like calcium or vitamin D) for a few days before testing, as they can affect results.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight sting, but the procedure is quick and typically painless. The blood sample is then sent to a lab for analysis.

What the Results Mean

While specific reference ranges vary by lab, higher-than-normal levels of vitamin D binding protein might indicate conditions like nephrotic syndrome or certain liver diseases. Lower-than-normal levels could be associated with kidney function issues or other metabolic disorders. Your results will be interpreted by your healthcare provider in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D binding protein plays a role in transporting vitamin D in the bloodstream. Abnormal levels may suggest underlying health concerns, such as kidney disease, liver disease, or conditions affecting protein synthesis. It can also be part of a broader assessment for vitamin D deficiency or its effects on bone health and immune function.

Short name

Vitamin D Binding Protein

Frequently asked questions

What causes vitamin D binding protein levels to change?
Changes in vitamin D binding protein levels can be influenced by kidney disease, liver disease, or certain genetic conditions. It may also fluctuate due to hormonal imbalances, malnutrition, or medications that affect protein production or metabolism.
Is there a simple way to check my vitamin D binding protein levels at home?
No, vitamin D binding protein tests are typically performed in a clinical lab using blood samples. Home testing kits are not available for this specific protein.
Can vitamin D binding protein levels be affected by diet?
While diet can influence overall protein levels in the blood, vitamin D binding protein itself is primarily produced by the liver and kidneys. However, certain dietary factors (like protein intake) may indirectly affect protein metabolism, though this is less direct than for other analytes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy