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Serum/plasma concentration of a specific protein marker for renal function (e.g., cystatin C)

Published: August 9, 2026Updated: August 16, 2026

This blood test measures cystatin C, a protein produced by cells throughout your body. It helps assess how well your kidneys are working.

Quick summary

["Cystatin C is a key marker for kidney function, often used alongside other tests like creatinine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100691-5
Short code
VZV DNA Bld NAA+probe-Log#
Synonyms
VZV DNA Bld NAA+probe-Log#
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for kidney problems, monitor kidney disease progression, or evaluate kidney function in people with other health conditions, such as diabetes or high blood pressure. It can also help determine if you need dialysis or other kidney treatments.

How Is the Test Performed?

A small blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is analyzed to measure cystatin C levels using a sensitive immunoassay or nephelometry method.

What Do Results Mean?

Higher than expected levels of cystatin C may suggest kidney damage or disease, while lower levels might indicate conditions that affect protein production or kidney function differently. Results are compared to a general reference range for your age and health status.

Common Conditions Monitored

This test is often used alongside creatinine tests to better assess kidney function, especially in people with chronic kidney disease, those on dialysis, or those with conditions like lupus, diabetes, or certain medications that can affect kidney health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Kidney Function and Beyond

Short name

Cystatin C (Serum/Plasma)

Frequently asked questions

What causes cystatin C levels to change?
Changes in cystatin C levels can be influenced by kidney disease, certain medications (like some antibiotics or chemotherapy drugs), pregnancy, or conditions that affect protein metabolism. It may also vary slightly with age or body composition.
Is this test the same as a creatinine test?
No, while both tests assess kidney function, cystatin C is generally more reliable for detecting early kidney damage and is often used in combination with creatinine to get a clearer picture of kidney health.
How soon will I get my results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will discuss them with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy