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Vitamin D Binding Protein (DBP) – Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of vitamin D binding protein in your blood serum. It helps assess how vitamin D is transported in your bloodstream.

Quick summary

["Understanding your vitamin D binding protein levels can support overall vitamin D metabolism evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100982-8
Short code
VZV DNA Spec NAA+probe-Log#
Synonyms
VZV DNA Spec NAA+probe-Log#
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if they suspect conditions affecting vitamin D metabolism, such as kidney disease, liver disease, or certain genetic disorders. It can also be part of a broader evaluation for vitamin D deficiency or related disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if instructed by your provider. Bring any medications or supplements you’re taking to your appointment.

During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick and typically painless. You can usually return to normal activities immediately afterward.

After the Test

After the blood draw, apply gentle pressure to the site to stop any bleeding. Apply a small bandage if needed. Avoid rubbing the area to prevent bruising. Most people experience minimal discomfort.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin D binding protein levels can be influenced by kidney function, liver health, and genetic factors. Abnormal levels may indicate conditions like nephrotic syndrome, liver disease, or hereditary disorders affecting protein synthesis. It can also help assess how well vitamin D is transported in your bloodstream, which is important for overall health, especially in conditions where vitamin D metabolism is compromised.

Short name

DBP Serum

Frequently asked questions

What does a high or low vitamin D binding protein level mean?
High levels may be associated with kidney disease, liver disease, or certain genetic conditions. Low levels could suggest normal function unless combined with other symptoms or test results.
Your provider will determine the frequency based on your medical history, symptoms, and other test results. It may be part of routine monitoring for certain conditions or performed as needed for evaluation.
Vitamin D binding protein itself is not directly affected by diet or supplements, but its function is indirectly tied to overall protein synthesis and kidney/liver health. Focus on maintaining a balanced diet and following your provider’s advice for managing any underlying conditions.
Is there any risk or side effect from this blood test?
The most common side effect is a slight bruise or minor discomfort at the injection site. Rarely, there may be a small risk of infection or excessive bleeding, but these are uncommon. Follow-up care may be needed if bleeding or excessive pain occurs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy