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Viral Zika Virus RNA Detection (Quantitative, Plasma/Serum)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from the Zika virus in your blood or plasma. It helps determine if you’ve recently been infected, even if you don’t yet have symptoms.

Quick summary

["Detects Zika virus RNA to guide infection diagnosis and management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49452-6
Short code
VZV DNA # Ur NAA+probe
Synonyms
VZV DNA # Ur NAA+probe
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for the genetic material (RNA) of the Zika virus in your blood or plasma. If present, it confirms a recent infection. This RNA may disappear over time, so results can change as your body clears the virus.

Why Your Doctor Might Order This Test

Your healthcare provider may recommend this test if you’ve traveled to or lived in an area with active Zika transmission, have symptoms like fever, rash, joint pain, or red eyes, or if you’re pregnant and exposed to Zika.

How the Test Works

A small blood or plasma sample is taken and analyzed using a specialized probe to detect Zika RNA. The test is highly sensitive and can identify infection even before symptoms appear.

What to Expect Before the Test

No special preparation is needed. You may have a quick blood draw, and results are typically available within a few days.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Zika RNA Probe

Frequently asked questions

How long does Zika RNA stay detectable in the blood?
Zika RNA may be detectable in the blood for days to weeks after infection, depending on the individual. Some people clear the virus faster, while others may have it longer. Your doctor will interpret results based on your symptoms and timeline of exposure.
Can I get tested if I’ve already had Zika?
If you’ve had Zika in the past, this test may not detect it. For past infections, your doctor might recommend antibody tests instead, which can show long-term immune response.
What if my test is positive?
A positive result means you likely have an active Zika infection. Your doctor will work with you to monitor symptoms, provide support, and guide next steps—especially if you’re pregnant or have health concerns related to Zika exposure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy