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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["This test helps evaluate liver health or protein-related conditions by tracking dye-protein interactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22603-5
Short code
VZV IgG sp1 Ser-aCnc
Synonyms
VZV IgG sp1 Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses bromocresol green dye, which binds to specific proteins in your blood. When the dye binds, it changes color, allowing the lab to estimate protein levels or liver function indirectly. This method is less common today but may still be used in certain clinical contexts.

Why It Might Be Ordered

Your healthcare provider may order this test if they suspect liver disease, protein disorders, or other conditions affecting protein synthesis. It can also be part of a broader evaluation for conditions like cirrhosis or malnutrition.

Sample Collection and Preparation

Blood is drawn from a vein, typically in your arm. The sample is processed to separate serum or plasma, which is then tested for dye binding properties. Results are compared to reference ranges for the protein concentration being assessed.

Interpretation of Results

Results are interpreted based on how much dye binds to proteins. Lower binding may indicate liver dysfunction or reduced protein production, while higher binding could suggest normal or elevated protein levels. Always discuss results with your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Dye Binding Assay

Frequently asked questions

How often will I need this test?
This test is not routinely performed in most clinical settings due to its limited use. It may be ordered occasionally for specific diagnostic purposes, such as evaluating liver function or protein metabolism. Your provider will determine if this test is necessary for your situation.
What are the typical reference ranges?
Reference ranges for this test are not widely standardized due to its niche use. Your results will be compared to the specific reference values used in your lab, which may vary. Your provider will explain what your results mean in the context of your health.
Are there any risks or side effects from this test?
Blood tests like this are generally safe. Possible side effects from the needle include mild bruising, soreness, or slight swelling at the injection site. If you experience any unusual reactions, contact your healthcare provider immediately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy