Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)
This test measures how bromocresol green dye binds to a protein in your blood, often used to assess liver function or protein synthesis.
["This test helps evaluate liver health or protein-related conditions by tracking dye-protein interactions."]
Key facts at a glance
- LOINC
- 22603-5
- Short code
- VZV IgG sp1 Ser-aCnc
- Synonyms
- VZV IgG sp1 Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test uses bromocresol green dye, which binds to specific proteins in your blood. When the dye binds, it changes color, allowing the lab to estimate protein levels or liver function indirectly. This method is less common today but may still be used in certain clinical contexts.
Why It Might Be Ordered
Your healthcare provider may order this test if they suspect liver disease, protein disorders, or other conditions affecting protein synthesis. It can also be part of a broader evaluation for conditions like cirrhosis or malnutrition.
Sample Collection and Preparation
Blood is drawn from a vein, typically in your arm. The sample is processed to separate serum or plasma, which is then tested for dye binding properties. Results are compared to reference ranges for the protein concentration being assessed.
Interpretation of Results
Results are interpreted based on how much dye binds to proteins. Lower binding may indicate liver dysfunction or reduced protein production, while higher binding could suggest normal or elevated protein levels. Always discuss results with your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
BCG Dye Binding Assay
Frequently asked questions
How often will I need this test?
What are the typical reference ranges?
Are there any risks or side effects from this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy