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Serum or Plasma Total Protein by Bromocresol Purple Photometric Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes albumin and other proteins like globulins.

Quick summary

["Total protein helps assess overall protein balance and kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14306-5
Short code
VZV IgG sp1 Ser IA-aCnc
Synonyms
VZV IgG sp1 Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions affecting protein levels, such as kidney disease, liver problems, malnutrition, or certain infections. It can also help diagnose or monitor conditions like nephrotic syndrome or protein-losing disorders.

What Does the Test Involve?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to determine the total protein concentration.

What Are Common Results and Their Meanings?

Higher-than-normal protein levels might suggest dehydration, multiple myeloma, or conditions that cause excessive protein production. Lower-than-normal levels could indicate malnutrition, liver disease, kidney disease, or severe burns.

How Is This Test Performed?

The test uses a photometric method with bromocresol purple dye to measure protein concentration in your serum or plasma. The dye binds to proteins, and the lab measures how much light is absorbed to calculate the protein amount.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels are important for diagnosing and managing several health conditions. Elevated levels may indicate conditions like dehydration, chronic inflammation, or certain cancers. Reduced levels can signal malnutrition, liver disease, kidney problems, or severe infections. Monitoring protein levels helps guide treatment plans for conditions like kidney disease or liver disorders.

Short name

Total Protein

Frequently asked questions

What causes high total protein levels?
High total protein levels can result from conditions such as dehydration, multiple myeloma, severe infections, or certain types of inflammation. Chronic diseases like kidney disease or liver cirrhosis may also contribute.
What causes low total protein levels?
Low total protein levels are often due to malnutrition, liver disease, kidney disease, or conditions causing excessive protein loss, such as severe burns or certain infections. Chronic conditions like cirrhosis or nephrotic syndrome can also lead to lower protein levels.
How often should I expect to have this test?
The frequency of this test depends on your medical condition and healthcare provider’s recommendations. Some patients may need it regularly to monitor kidney or liver function, while others may only need it once for diagnostic purposes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy