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Serum or plasma mass concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Bilirubin levels can signal liver or bile system issues, including jaundice or gallbladder problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95714-2
Short code
VZV IgG Spec IA-aCnc
Synonyms
VZV IgG Spec IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order this test to check for liver disease, bile duct problems, or conditions causing jaundice (yellowing of skin/eyes). It can also help diagnose or monitor conditions like hemolytic anemia, cirrhosis, or hepatitis.

What to expect before the test

No special preparation is needed. You may have a blood draw from a vein in your arm, or a urine sample may be collected if testing is done at home (e.g., for newborn screening).

What does the test involve?

Blood is drawn (serum/plasma) or urine is collected. The sample is sent to a lab where bilirubin levels are measured using a specialized method to determine its concentration.

What are common results?

Results are reported as a mass concentration value (e.g., micrograms per deciliter). Higher than normal levels may indicate liver or bile system problems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin level

Frequently asked questions

What causes high bilirubin levels?
High bilirubin can result from liver problems (e.g., hepatitis), bile duct blockages, or increased red blood cell breakdown (e.g., anemia). It may also appear in newborns due to immature liver function.
What causes low bilirubin levels?
Low bilirubin is usually normal but can occur with certain blood disorders or liver conditions. Rarely, it may indicate liver disease if other symptoms are present.
How often should I get this test?
Your doctor will determine frequency based on your health. Regular tests may be needed if you have liver disease, jaundice, or other conditions requiring monitoring.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy