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Serum or Plasma Substance Concentration (Electrochemiluminescence Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a particular protein in your blood, using a sensitive electrochemical detection method. It helps assess conditions related to protein function, immune response, or metabolic processes.

Quick summary

["This test helps diagnose or monitor conditions affecting protein levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6569-8
Short code
VZV IgG Titr Ser IF
Synonyms
VZV IgG Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate symptoms such as unexplained fatigue, organ dysfunction, or signs of an underlying medical condition. It can also be used to monitor treatment progress or check for changes in protein levels over time. Common reasons include investigating autoimmune disorders, kidney disease, liver issues, or genetic conditions affecting protein metabolism.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours if the test involves a specific timing (e.g., 24-hour collection). Avoid smoking or consuming certain medications for a set period before testing. Bring any medications you’re currently taking to your appointment.

During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch or discomfort, but it usually lasts only a few seconds. The process takes about 5 minutes. If you’re nervous, let your provider know—they can offer ways to stay calm.

After the Test

You can return to your normal activities immediately. Apply gentle pressure to the site to stop any bleeding, and check the area for signs of infection (e.g., redness, swelling). Avoid heavy lifting or strenuous activity for a short time. Call your provider if you experience excessive pain, swelling, or signs of infection.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Electrochemiluminescence Immunoassay (ECLIA) for a Specific Protein

Frequently asked questions

This test helps identify abnormal protein levels that may indicate conditions like chronic kidney disease, liver disease, or autoimmune disorders. Elevated or low levels can signal problems with protein synthesis, breakdown, or transport in the body. For example, certain proteins are linked to immune function, muscle health, or fluid balance. Early detection can guide treatment decisions.
What does a high or low result mean?
A result outside the expected range may not have a straightforward interpretation. Your provider will review your results alongside your medical history, symptoms, and other tests to determine if further action is needed. Some proteins have specific roles, so abnormal levels could point to conditions like protein-losing syndromes, infections, or genetic disorders.
Can I eat or drink before this test?
Most likely, no fasting is required unless specified by your provider. If the test involves a 24-hour urine collection or other specific instructions, follow those carefully. Always confirm with your healthcare team before making changes to your diet or medications.
Results are typically available within 24 to 72 hours, depending on lab processing times. Your provider will contact you once results are ready. If you have urgent concerns, ask your healthcare team about expected turnaround times.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy