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Serum or plasma concentration of vitamin K-dependent coagulation factor (e.g., protein C)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specific protein involved in blood clotting. It helps assess how well your blood can clot normally.

Quick summary

["Helps identify bleeding disorders or clotting risks linked to protein C deficiency or dysfunction."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31695-0
Short code
VZV IgM CSF-aCnc
Synonyms
VZV IgM CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

Your blood sample is tested for the presence of protein C, a natural anticoagulant that helps prevent abnormal blood clots. The test checks its concentration in your serum or plasma.

Why It Matters in Medicine

Protein C plays a critical role in maintaining blood flow by preventing clots from forming where they shouldn’t. Low levels can increase the risk of clotting disorders, while high levels may suggest certain blood disorders.

Common Reasons for Testing

Doctors may order this test if you have symptoms of bleeding problems (e.g., easy bruising, excessive bleeding), a history of clotting disorders, or if you’re taking blood thinners. It’s also used in monitoring conditions like thrombophilia or after trauma.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where it’s separated into serum (liquid part after clotting) or plasma (liquid part before clotting). The protein C level is then measured using a specialized immunoassay or similar method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Factor C Level

Frequently asked questions

Why might my protein C levels be checked?
Your doctor may recommend this test if you have a family history of clotting issues, recent surgery, or symptoms like unexplained bruising or bleeding. It’s also part of evaluating conditions like disseminated intravascular coagulation (DIC) or inherited clotting disorders.
What do my results mean?
Results are compared to a standard range, but exact values can vary by lab. Low levels may indicate a clotting disorder, while very high levels could suggest liver disease or other conditions. Always discuss your results with your healthcare provider.
How can I prepare for this test?
No special preparation is usually needed, but avoid aspirin or certain blood thinners for a few days before testing if directed by your doctor. Wear comfortable clothing for the blood draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy