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Serum or plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice.

Quick summary

["Your doctor may check bilirubin levels to diagnose or monitor liver or bile duct issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
69930-6
Short code
VZV IgM CSF Ql IA
Synonyms
VZV IgM CSF Ql IA
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for liver problems, such as hepatitis, cirrhosis, or bile duct blockages. It can also help diagnose conditions like Gilbert syndrome or monitor treatment for certain diseases.

What Does an Abnormal Result Mean?

High bilirubin levels (hyperbilirubinemia) can indicate liver disease, red blood cell disorders, or blockages in the bile ducts. Low levels are less common but may occur with certain liver conditions or medications.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab where it is analyzed to measure bilirubin concentration using a specialized method, often automated and precise.

What Are Common Causes?

Common causes of elevated bilirubin include liver diseases (like hepatitis), gallstones blocking bile flow, hemolytic anemia (where red blood cells break down too quickly), and certain medications or genetic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated bilirubin levels can cause yellowing of the skin and eyes (jaundice), dark urine, or pale stools. Low levels may not cause noticeable symptoms but could be linked to underlying liver or metabolic issues.

Short name

Total bilirubin

Frequently asked questions

How often should I expect to have this test?
The frequency depends on your health condition and why the test was ordered. Some people may need it once, while others may have it regularly if they have ongoing liver or blood-related issues.
What can I do to prepare for this test?
No special preparation is usually needed, but avoid heavy meals before the blood draw. If you’re taking medications that affect liver function, let your healthcare provider know.
Does this test hurt?
The blood draw itself may cause a slight sting or discomfort, but most people find it brief and manageable. You may feel a pinch when the needle is inserted, but the area will heal quickly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy