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Serum or plasma mass concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Your doctor may order this test to check liver health or identify causes of yellowing skin/eyes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17766-7
Short code
VZV IgM Ser IF-aCnc
Synonyms
VZV IgM Ser IF-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may request a total bilirubin test to diagnose or monitor conditions affecting the liver, bile ducts, or red blood cells. It can also help identify issues like hepatitis, gallstones, or hemolytic anemia. Sometimes, it’s part of routine liver function tests.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel. Bring any medications you’re taking, as some (like certain pain relievers) can affect results.

How the Test Works

A blood sample is drawn from a vein in your arm. The lab separates serum or plasma and measures bilirubin levels using a colorimetric method, which detects its presence through light absorption.

Possible Results and Interpretation

High bilirubin levels (hyperbilirubinemia) may indicate liver disease, bile duct problems, or red blood cell disorders. Low levels are less common but could signal liver dysfunction or certain genetic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

What causes high bilirubin levels?
High bilirubin can result from liver problems (like hepatitis or cirrhosis), blockages in the bile ducts, or rapid red blood cell breakdown (hemolysis). Lifestyle factors (e.g., alcohol use) or certain medications may also play a role.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing speed. Your doctor will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
If fasting is required (e.g., for a liver panel), avoid food and liquids (except water) for 8–12 hours beforehand. If no fasting is needed, you can eat normally, but check with your doctor first.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy