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Vitamin D Binding Protein (DBP) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of vitamin D binding protein, a protein in your blood that helps transport vitamin D and other fat-soluble vitamins. It may be ordered to assess vitamin D metabolism or related conditions.

Quick summary

["Your vitamin D binding protein levels can help doctors understand how your body processes vitamin D and other fat-soluble vitamins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10734-2
Short code
VZV Skin EM
Synonyms
VZV Skin EM
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
microscopy-electron
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect conditions affecting vitamin D metabolism, such as kidney disease, liver disease, or certain genetic disorders. It may also be part of a broader evaluation for vitamin D deficiency or related disorders, though vitamin D itself is often measured separately.

What to Expect Before the Test

No special preparation is usually needed for this test. You may have a blood sample drawn from a vein in your arm, similar to other routine blood tests. If you’re on blood thinners or have a history of bleeding disorders, let your provider know before the test.

What the Test Results Mean

Vitamin D binding protein levels can vary based on health conditions, genetics, and other factors. While elevated or low levels may indicate certain health concerns, they are not diagnostic on their own. Your provider will interpret results in the context of your overall health and other tests.

Common Conditions Monitored or Investigated

This test may be used to help diagnose or monitor conditions like hereditary vitamin D deficiency disorders, kidney disease, or liver disease. It can also provide insight into how well your body is transporting certain vitamins.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Vitamin D Binding Protein Level

Frequently asked questions

What causes abnormal vitamin D binding protein levels?
Abnormal levels of vitamin D binding protein can be influenced by genetic factors, kidney disease, liver disease, or certain medications. Conditions like hereditary vitamin D-binding protein deficiency or other metabolic disorders may also play a role. However, many factors can affect protein levels, so results should be reviewed by your healthcare provider.
How often should I get this test?
The frequency of this test depends on your health condition and medical history. Your provider will determine if and how often you need testing based on your specific needs, such as monitoring chronic kidney or liver disease, or evaluating suspected genetic disorders.
Can diet or supplements affect vitamin D binding protein levels?
While diet and supplements can influence overall vitamin D levels, they may not directly affect vitamin D binding protein levels. However, certain medications (e.g., steroids, anticonvulsants) or chronic illnesses may impact protein levels. Always discuss any changes in your health or medications with your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy