Serum or plasma concentration of bile acids (total)

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like abdominal pain, jaundice (yellowing of skin/eyes), unexplained fatigue, or if they suspect liver disease, gallbladder problems, or bile duct blockages. It can also be part of routine evaluations for conditions like cirrhosis, hepatitis, or bile acid malabsorption.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel. Bring any medications you’re taking, as some (like bile acid medications) could affect results.

What the Test Involves

A blood sample will be drawn from a vein in your arm. The blood is then sent to a lab to measure the total concentration of bile acids, which are organic compounds produced by the liver and stored in the gallbladder.

Possible Results and Their Meaning

Higher-than-normal levels may indicate liver disease, gallbladder issues, or bile duct obstructions. Lower-than-normal levels could suggest bile acid malabsorption (e.g., from Crohn’s disease, celiac disease, or pancreatic disorders). Your provider will interpret results in the context of your symptoms and other tests.